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A novel inflammasome-independent role for epithelial expressed Nlrp3 in renal ischemia-reperfusion injury

Cytoplasmic innate immune receptors are important therapeutic targets for diseases associated with overproduction of proinflammatory cytokines. One cytoplasmic receptor complex, the Nlrp3 inflammasome, responds to an extensive array of molecules associated with cellular stress. Under normal conditio...

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Detalhes bibliográficos
Main Authors: Shigeoka, Alana A., Mueller, James L., Kambo, Amanpreet, Mathison, John C., King, Andrew J., Hall, Wesley F., da Silva Correia, Jean, Ulevitch, Richard J., Hoffman, Hal M., McKay, Dianne B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020135/
https://ncbi.nlm.nih.gov/pubmed/20962258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002330
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