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Bypassing of stems versus linear base-by-base inspection of mammalian mRNAs during ribosomal scanning
Initiation codon selection in eukaryotes involves base-by-base inspection of the 5′-untranslated region of mRNA by scanning ribosomal 43S preinitiation complexes. We employed in vitro reconstitution to investigate factor requirements for this process and report that in the absence of eIF1 and DHX29,...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3020121/ https://ncbi.nlm.nih.gov/pubmed/21113134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.302 |
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