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Identifying a Transcription Factor’s Regulatory Targets from its Binding Targets

ChIP-chip data, which shows binding of transcription factors (TFs) to promoter regions in vivo, are widely used by biologists to identify the regulatory targets of TFs. However, the binding of a TF to a gene does not necessarily imply regulation. Thus, it is important to develop computational method...

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Detalhes bibliográficos
Main Authors: Lai, Fred, Chang, Julie S., Wu, Wei-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020039/
https://ncbi.nlm.nih.gov/pubmed/21245946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/GRSB.S6458
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