The Receptor-Binding Domain of Influenza Virus Hemagglutinin Produced in Escherichia coli Folds into Its Native, Immunogenic Structure

The hemagglutinin (HA) surface glycoprotein promotes influenza virus entry and is the key protective antigen in natural immunity and vaccines. The HA protein is a trimeric envelope glycoprotein consisting of a globular receptor-binding domain (HA-RBD) that is inserted into a membrane fusion-mediatin...

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Bibliografiske detaljer
Main Authors: DuBois, Rebecca M., Aguilar-Yañez, José Manuel, Mendoza-Ochoa, Gonzalo I., Oropeza-Almazán, Yuriana, Schultz-Cherry, Stacey, Alvarez, Mario Moisés, White, Stephen W., Russell, Charles J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2011
Fag:
Structure and Assembly
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020035/
https://ncbi.nlm.nih.gov/pubmed/21068239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01412-10
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