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The Kaposi's Sarcoma-Associated Herpesvirus G Protein-Coupled Receptor Contains an Immunoreceptor Tyrosine-Based Inhibitory Motif That Activates Shp2

The Kaposi's sarcoma-associated herpesvirus (KSHV) G protein-coupled receptor (vGPCR) is a constitutively active, highly angiogenic homologue of the interleukin-8 (IL-8) receptors that signals in part via the cytoplasmic protein tyrosine phosphatase Shp2. We show that vGPCR contains a bona fide...

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Bibliografske podrobnosti
Main Authors: Philpott, Nicola, Bakken, Thomas, Pennell, Christopher, Chen, Liwei, Wu, Jie, Cannon, Mark
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020031/
https://ncbi.nlm.nih.gov/pubmed/21047965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01362-10
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