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Inhibition of Calmodulin-Dependent Kinase Kinase Blocks Human Cytomegalovirus-Induced Glycolytic Activation and Severely Attenuates Production of Viral Progeny

Viruses depend on the host cell to provide the energy and biomolecular subunits necessary for production of viral progeny. We have previously reported that human cytomegalovirus (HCMV) infection induces dramatic changes to central carbon metabolism, including glycolysis, the tricarboxylic acid (TCA)...

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Detalhes bibliográficos
Main Authors: McArdle, Jessica, Schafer, Xenia L., Munger, Joshua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019999/
https://ncbi.nlm.nih.gov/pubmed/21084482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01557-10
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