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Expression of Oncogenic Alleles Induces Multiple Blocks to Human Cytomegalovirus Infection

In contrast to many viruses, human cytomegalovirus (HCMV) is unable to productively infect most cancer-derived cell lines. The mechanisms of this restriction are unclear. To explore this issue, we tested whether defined oncogenic alleles, including the simian virus 40 (SV40) T antigen (TAg) and onco...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Xu, Shihao, Schafer, Xenia, Munger, Joshua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836323/
https://ncbi.nlm.nih.gov/pubmed/26889030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00179-16
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