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Strain-Specific Polymorphisms in Paneth Cell α-Defensins of C57BL/6 Mice and Evidence of Vestigial Myeloid α-Defensin Pseudogenes

Paneth cells at the base of small intestinal crypts secrete microbicidal α-defensins, termed cryptdins (Crps) in mice, as mediators of innate immunity. Proteomic studies show that five abundant Paneth cell α-defensins in C57BL/6 mice are strain specific in that they have not been identified in other...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shanahan, Michael T., Tanabe, Hiroki, Ouellette, André J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019906/
https://ncbi.nlm.nih.gov/pubmed/21041494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00996-10
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