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Requirement for Class II Phosphoinositide 3-Kinase C2α in Maintenance of Glomerular Structure and Function

An early lesion in many kidney diseases is damage to podocytes, which are critical components of the glomerular filtration barrier. A number of proteins are essential for podocyte filtration function, but the signaling events contributing to development of nephrotic syndrome are not well defined. He...

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Autors principals: Harris, David P., Vogel, Peter, Wims, Marie, Moberg, Karen, Humphries, Juliane, Jhaver, Kanchan G., DaCosta, Christopher M., Shadoan, Melanie K., Xu, Nianhua, Hansen, Gwenn M., Balakrishnan, Sanjeevi, Domin, Jan, Powell, David R., Oravecz, Tamas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019860/
https://ncbi.nlm.nih.gov/pubmed/20974805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00468-10
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