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The Yeast-Phase Virulence Requirement for α-Glucan Synthase Differs among Histoplasma capsulatum Chemotypes

Histoplasma capsulatum strains can be classified into two chemotypes based on cell wall composition. The cell wall of chemotype II yeast contains a layer of α-(1,3)-glucan that masks immunostimulatory β-(1,3)-glucans from detection by the Dectin-1 receptor on host phagocytes. This α-(1,3)-glucan cel...

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Detalles Bibliográficos
Main Authors: Edwards, Jessica A., Alore, Elizabeth A., Rappleye, Chad A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019800/
https://ncbi.nlm.nih.gov/pubmed/21037179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00214-10
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