Intranasal Vaccination with Chitosan-DNA Nanoparticles Expressing Pneumococcal Surface Antigen A Protects Mice against Nasopharyngeal Colonization by Streptococcus pneumoniae

Streptococcus pneumoniae is a respiratory pathogen, and mucosal immune response plays a significant role in the defense against pneumococcal infections. Thus, intranasal vaccination may be an alternative approach to current immunization strategies, and effective delivery systems to mucosal organism...

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Detalhes bibliográficos
Main Authors: Xu, Jianghong, Dai, Wenjia, Wang, Zhengmin, Chen, Bing, Li, Zhongming, Fan, Xiaoyong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019786/
https://ncbi.nlm.nih.gov/pubmed/21047997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00263-10
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