Multilaboratory Comparison of Streptococcus pneumoniae Opsonophagocytic Killing Assays and Their Level of Agreement for the Determination of Functional Antibody Activity in Human Reference Sera

Antibody-mediated killing of Streptococcus pneumoniae (pneumococcus) by phagocytes is an important mechanism of protection of the human host against pneumococcal infections. Measurement of opsonophagocytic antibodies by use of a standardized opsonophagocytic assay (OPA) is important for the evaluati...

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Main Authors: Rose, Charles E., Romero-Steiner, Sandra, Burton, Robert L., Carlone, George M., Goldblatt, David, Nahm, Moon H., Ashton, Lindsey, Haston, Mitch, Ekström, Nina, Haikala, Raili, Käyhty, Helena, Henckaerts, Isabelle, Durant, Nathalie, Poolman, Jan T., Fernsten, Phil, Yu, Xinhong, Hu, Branda T., Jansen, Kathrin U., Blake, Milan, Simonetti, Elles R., Hermans, Peter W. M., Plikaytis, Brian D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Microbial Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019776/
https://ncbi.nlm.nih.gov/pubmed/21084458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00370-10
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