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Bmi-1 is a Crucial Regulator of Prostate Stem Cell Self-Renewal and Malignant Transformation
The Polycomb group transcriptional repressor Bmi-1 is often up-regulated in prostate cancer, but its functional roles in prostate stem cell maintenance and prostate cancer are unclear. Loss- and gain-of-function analysis in a prostate sphere assay indicates that Bmi-1 expression is required for self...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3019762/ https://ncbi.nlm.nih.gov/pubmed/21112563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.11.013 |
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