Mutant feedback-resistant phosphoribosylpyrophosphate synthetase associated with purine overproduction and gout. Phosphoribosylpyrophosphate and purine metabolism in cultured fibroblasts.

We have reported previously two siblings with gout and uric acid lithiasis associated with excessive purine production. In the erythrocytes of these patients, phosphoribosylpyrophosphate (PRPP) synthetase exhibited resistance to feedback-inhibition by normal cell constituents such as guanosine-5...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Zoref, E, De Vries, A, Sperling, O
Format: Artigo
Jezik:Inglês
Izdano: 1975
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC301970/
https://ncbi.nlm.nih.gov/pubmed/171280
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items