Structural and Biochemical Analysis of the Pentapeptide Repeat Protein EfsQnr, a Potent DNA Gyrase Inhibitor

The chromosomally encoded Qnr homolog protein from Enterococcus faecalis (EfsQnr), when expressed, confers to its host a decreased susceptibility to quinolones and consists mainly of tandem repeats, which is consistent with belonging to the pentapeptide repeat family of proteins (PRPs). EfsQnr was c...

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Bibliografiske detaljer
Main Authors: Hegde, Subray S., Vetting, Matthew W., Mitchenall, Lesley A., Maxwell, Anthony, Blanchard, John S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2011
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019687/
https://ncbi.nlm.nih.gov/pubmed/20937785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01158-10
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