Mode-of-Action Studies of the Novel Bisquaternary Bisnaphthalimide MT02 against Staphylococcus aureus

Screening of various bisquaternary bisnaphthalimides against a variety of human pathogens revealed one compound, designated MT02, with strong inhibitory effects against Gram-positive bacteria. The MICs ranged from 0.31 μg/ml against community-acquired methicillin-resistant Staphylococcus aureus (MRS...

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Main Authors: Menzel, Thomas M., Tischer, Maximilian, François, Patrice, Nickel, Joachim, Schrenzel, Jacques, Bruhn, Heike, Albrecht, Annette, Lehmann, Leane, Holzgrabe, Ulrike, Ohlsen, Knut
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2011
Teme:
Mechanisms of Action: Physiological Effects
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019648/
https://ncbi.nlm.nih.gov/pubmed/20937782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00586-10
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