The surface variant antigens of Plasmodium falciparum contain cross-reactive epitopes

Plasmodium falciparum parasites evade the host immune system by clonal expression of the variant antigen, P. falciparum erythrocyte membrane protein 1 (PfEMP1). Antibodies to PfEMP1 correlate with development of clinical immunity but are predominantly variant-specific. To overcome this major limitat...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Gamain, Benoit, Miller, Louis H., Baruch, Dror I.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2001
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30195/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11226296/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.041602598
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