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The surface variant antigens of Plasmodium falciparum contain cross-reactive epitopes

Plasmodium falciparum parasites evade the host immune system by clonal expression of the variant antigen, P. falciparum erythrocyte membrane protein 1 (PfEMP1). Antibodies to PfEMP1 correlate with development of clinical immunity but are predominantly variant-specific. To overcome this major limitat...

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Bibliographic Details
Main Authors: Gamain, Benoit, Miller, Louis H., Baruch, Dror I.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC30195/
https://ncbi.nlm.nih.gov/pubmed/11226296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.041602598
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