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Insulin Receptor Deficiency in Genetic and Acquired Obesity

We have previously shown that in the insulin-resistant obese hyperglycemic mouse (ob/ob) there is a deficiency in the number of insulin receptor sites on hepatocytes, adipocytes, and thymic lymphocytes. We now find that concentration of insulin receptors on liver plasma membranes is decreased in the...

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Pubblicato in:J Clin Invest
Autori principali: Soli, Andrew H., Kahn, C. Ronald, Neville, David M., Roth, Jesse
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1975
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301931/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/169296/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108155
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