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Identification of Critical Residues of the Mycobacterial Dephosphocoenzyme A Kinase by Site-Directed Mutagenesis
Dephosphocoenzyme A kinase performs the transfer of the γ-phosphate of ATP to dephosphocoenzyme A, catalyzing the last step of coenzyme A biosynthesis. This enzyme belongs to the P-loop-containing NTP hydrolase superfamily, all members of which posses a three domain topology consisting of a CoA doma...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Public Library of Science
2011
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3019153/ https://ncbi.nlm.nih.gov/pubmed/21264299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015228 |
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