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Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous System

Obesity is a growing epidemic characterized by excess fat storage in adipocytes. Although lipoprotein receptors play important roles in lipid uptake, their role in controlling food intake and obesity is not known. Here we show that the lipoprotein receptor LRP1 regulates leptin signaling and energy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Qiang, Zhang, Juan, Zerbinatti, Celina, Zhan, Yan, Kolber, Benedict J., Herz, Joachim, Muglia, Louis J., Bu, Guojun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019112/
https://ncbi.nlm.nih.gov/pubmed/21264353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000575
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