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Targeting Notch pathway induces growth inhibition and differentiation of neuroblastoma cells
High-risk neuroblastoma is a severe pediatric tumor characterized by poor prognosis. Understanding the molecular mechanisms involved in tumor development and progression is strategic for the improvement of pharmacological therapies. Notch was recently proposed as a pharmacological target for the the...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018939/ https://ncbi.nlm.nih.gov/pubmed/20716592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq101 |
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