Targeting Notch pathway induces growth inhibition and differentiation of neuroblastoma cells

High-risk neuroblastoma is a severe pediatric tumor characterized by poor prognosis. Understanding the molecular mechanisms involved in tumor development and progression is strategic for the improvement of pharmacological therapies. Notch was recently proposed as a pharmacological target for the the...

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Hlavní autoři: Ferrari-Toninelli, Giulia, Bonini, Sara Anna, Uberti, Daniela, Buizza, Laura, Bettinsoli, Paola, Poliani, Pietro Luigi, Facchetti, Fabio, Memo, Maurizio
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018939/
https://ncbi.nlm.nih.gov/pubmed/20716592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq101
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