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Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-γ gene and protein expression in lupus T cells
In systemic lupus erythematosus (SLE), T helper cells exhibit increased and prolonged expression of cell-surface CD40 ligand (CD154), spontaneously overproduce interleukin-10 (IL-10), but underproduce interferon-gamma (IFN-γ). We tested the hypothesis that the imbalance of these gene products reflec...
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Autors principals: | , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
The National Academy of Sciences
2001
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC30189/ https://ncbi.nlm.nih.gov/pubmed/11226290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051507098 |
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