Molecular Basis of Evolutionary Loss of the α1,3-Galactosyltransferase Gene in Higher Primates

Galactose-α1,3-galactose(αGal) epitopes, the synthesis of which requires the enzyme product of α1,3-galactosyltransferase (α1,3GT), are sugar chains on the cell surface of most mammalian species. Notable exceptions are higher primates including Old World monkeys, apes, and humans. The αGal-negative...

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Main Authors: Koike, Chihiro, Fung, John J., Geller, David A., Kannagi, Reiji, Libert, Therese, Luppi, Patrizia, Nakashima, Izumi, Profozich, Jennifer, Rudert, William, Sharma, Sugandha B., Starzl, Thomas E., Trucco, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018882/
https://ncbi.nlm.nih.gov/pubmed/11773054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110527200
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