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Ladder Polyether Synthesis via Epoxide-Opening Cascades Directed by a Disappearing Trimethylsilyl Group

Epoxide-opening cascades offer the potential to construct complex polyether natural products expeditiously and in a manner that emulates the biogenesis proposed for these compounds. Herein we provide a full account of our development of a strategy that addresses several important challenges of such...

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Detalhes bibliográficos
Main Authors: Heffron, Timothy P., Simpson, Graham L., Merino, Estibaliz, Jamison, Timothy F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018858/
https://ncbi.nlm.nih.gov/pubmed/20302314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo1002455
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