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The TWEAK–Fn14 cytokine–receptor axis: discovery, biology and therapeutic targeting
TWEAK is a multifunctional cytokine that controls many cellular activities including proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK acts by binding to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathway...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018765/ https://ncbi.nlm.nih.gov/pubmed/18404150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd2488 |
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