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Dynamics and Mechanism of Repair of UV-induced (6-4) Photoproduct by Photolyase
One of the detrimental effects of UV radiation on DNA is the formation of the (6-4) photoproduct (6-4PP) between two adjacent pyrimidines1. This lesion interferes with replication and transcription and may result in mutation and cell death2. In many organisms a flavoenzyme called photolyase uses blu...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018752/ https://ncbi.nlm.nih.gov/pubmed/20657578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09192 |
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