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A truncated HGP peptide sequence retains endosomolytic activity and improves gene delivery efficiencies
HGP is a 24-amino acid peptide derived from HIV gp41 that increases vesicular escape when incorporated into gene delivery vehicles. The typical yield of HGP from solid phase peptide synthesis is low due to its length and hydrophobicity. The goal of this work was to investigate truncated sequences th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018701/ https://ncbi.nlm.nih.gov/pubmed/20476763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp1000668 |
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