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Essential Role of Toll-Like Receptor 2 in Morphine-Induced Microglia Activation in Mice

Opioids are powerful pain relievers, but also potent inducers of dependence and tolerance. Chronic morphine administration (via subcutaneous pellet) induces morphine dependence in the nucleus accumbens, an important dependence region in the brain, yet the cellular mechanisms are mostly unknown. Toll...

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Autors principals: Zhang, Yi, Li, Hui, Li, Yi, Sun, Xiuli, Zhu, Mengyang, Hanley, Gregory, LeSage, Gene, Yin, Deling
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018547/
https://ncbi.nlm.nih.gov/pubmed/21130144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.11.063
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