Associations of Plasma Selenium with Arsenic and Genomic Methylation of Leukocyte DNA in Bangladesh

BACKGROUND: Global hypomethylation of DNA is thought to constitute an early event in some cancers and occurs in response to arsenic (As) exposure and/or selenium (Se) deficiency in both in vitro and animal models. In addition, antagonism between As and Se, whereby each reduces toxicity of the other,...

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Main Authors: Pilsner, J. Richard, Hall, Megan N., Liu, Xinhua, Ahsan, Habibul, Ilievski, Vesna, Slavkovich, Vesna, Levy, Diane, Factor-Litvak, Pam, Graziano, Joseph H., Gamble, Mary V.
Format: Artigo
Language:Inglês
Published: National Institute of Environmental Health Sciences 2011
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018489/
https://ncbi.nlm.nih.gov/pubmed/21205583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1001937
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