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Top-Down Protein Characterization Facilitated by Ion/Ion Reactions on a Quadrupole/Time-of-Flight Platform

In comparison to bottom-up proteomics approaches, whereby peptides derived from proteolytic digestion are analyzed, top-down approaches, involving direct analysis of intact proteins, provides higher specificity for protein identification and are better-suited for the characterization of sequence var...

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Bibliografische gegevens
Hoofdauteurs: Huang, Teng-yi, McLuckey, Scott A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018239/
https://ncbi.nlm.nih.gov/pubmed/20848674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201000187
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