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Top-Down Protein Characterization Facilitated by Ion/Ion Reactions on a Quadrupole/Time-of-Flight Platform
In comparison to bottom-up proteomics approaches, whereby peptides derived from proteolytic digestion are analyzed, top-down approaches, involving direct analysis of intact proteins, provides higher specificity for protein identification and are better-suited for the characterization of sequence var...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018239/ https://ncbi.nlm.nih.gov/pubmed/20848674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201000187 |
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