Limited Contribution of Mucosal IgA to Simian Immunodeficiency Virus (SIV)-Specific Neutralizing Antibody Response and Virus Envelope Evolution in Breast Milk of SIV-Infected, Lactating Rhesus Monkeys

Breast milk transmission of human immunodeficiency virus (HIV) remains an important mode of infant HIV acquisition. Interestingly, the majority of infants remain uninfected during prolonged virus exposure via breastfeeding, raising the possibility that immune components in milk prevent mucosal virus...

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Autori principali: Permar, Sallie R., Wilks, Andrew B., Ehlinger, Elizabeth P., Kang, Helen H., Mahlokozera, Tatenda, Coffey, Rory T., Carville, Angela, Letvin, Norman L., Seaman, Michael S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017679/
https://ncbi.nlm.nih.gov/pubmed/21041730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002751
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