Limited Contribution of Mucosal IgA to Simian Immunodeficiency Virus (SIV)-Specific Neutralizing Antibody Response and Virus Envelope Evolution in Breast Milk of SIV-Infected, Lactating Rhesus Monkeys

Breast milk transmission of human immunodeficiency virus (HIV) remains an important mode of infant HIV acquisition. Interestingly, the majority of infants remain uninfected during prolonged virus exposure via breastfeeding, raising the possibility that immune components in milk prevent mucosal virus...

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Main Authors: Permar, Sallie R., Wilks, Andrew B., Ehlinger, Elizabeth P., Kang, Helen H., Mahlokozera, Tatenda, Coffey, Rory T., Carville, Angela, Letvin, Norman L., Seaman, Michael S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916548/
https://ncbi.nlm.nih.gov/pubmed/20519381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00656-10
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