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Interaction and co-localization of JC virus large T antigen and the F-box protein β-transducin-repeat containing protein

Lytic infection and transformation of cultured cells by JC virus (JCV) require five tumor proteins, which interact with factors regulating critical cellular processes. We demonstrate that JCV large T antigen (TAg) binds the F-box proteins β-transducin-repeat containing protein-1 and 2 (βTrCP1/2). Th...

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Main Authors: Reviriego-Mendoza, Marta M., Frisque, Richard J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017642/
https://ncbi.nlm.nih.gov/pubmed/21106215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.10.038
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