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JC Virus Small t Antigen Binds Phosphatase PP2A and Rb Family Proteins and Is Required for Efficient Viral DNA Replication Activity

BACKGROUND: The human polyomavirus, JC virus (JCV) produces five tumor proteins encoded by transcripts alternatively spliced from one precursor messenger RNA. Significant attention has been given to replication and transforming activities of JCV's large tumor antigen (TAg) and three T′ proteins...

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Detalhes bibliográficos
Main Authors: Bollag, Brigitte, Hofstetter, Catherine A., Reviriego-Mendoza, Marta M., Frisque, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868895/
https://ncbi.nlm.nih.gov/pubmed/20485545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010606
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