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The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesion

DNA double-stranded breaks (DSBs) are among the most severe forms of DNA damage and responsible for chromosomal translocations that may lead to gene fusions. The RAD51 family plays an integral role in preserving genome stability by homology directed repair of DSBs. From a proteomics screen, we recen...

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Bibliografiska uppgifter
Huvudupphovsmän: Rajesh, Changanamkandath, Baker, Dustin K., Pierce, Andrew J., Pittman, Douglas L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017596/
https://ncbi.nlm.nih.gov/pubmed/20813759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq738
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