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Interacting JNK-docking Sites in MKK7 Promote Binding and Activation of JNK Mitogen-activated Protein Kinases

D-sites are a class of MAPK-docking sites that have been found in many MAPK regulators and substrates. A single functional, high affinity D-site has been identified near the N terminus of each of the MAPK kinases (MKKs or MEKs) MEK1, MEK2, MKK3, MKK4, and MKK6. Here we demonstrated that MKK7 recogni...

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Detalhes bibliográficos
Main Authors: Ho, David T., Bardwell, A. Jane, Grewal, Seema, Iverson, Corey, Bardwell, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017509/
https://ncbi.nlm.nih.gov/pubmed/16533805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M601010200
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