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A Docking Site in MKK4 Mediates High Affinity Binding to JNK MAPKs and Competes with Similar Docking Sites in JNK Substrates
Specific docking interactions between MAPKs and their activating MAPK kinases (MKKs or MEKs) are crucial for efficient and accurate signal transmission. Here, we report the identification of a MAPK-docking site, or “D-site,” in the N terminus of human MKK4/JNKK1. This docking site conforms to the co...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017503/ https://ncbi.nlm.nih.gov/pubmed/12788955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M304229200 |
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