Interaction of a transcriptional repressor with the RNA polymerase II holoenzyme plays a crucial role in repression

The yeast transcriptional repressor Tup1, tethered to DNA, represses to strikingly different degrees transcription elicited by members of two classes of activators. Repression in both cases is virtually eliminated by mutation of either member of the cyclin-kinase pair Srb10/11. In contrast, telomeri...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Zaman, Zafar, Ansari, Aseem Z., Koh, Sang Seok, Young, Richard, Ptashne, Mark
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30175/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11226276/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.041611198
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