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Interaction of a transcriptional repressor with the RNA polymerase II holoenzyme plays a crucial role in repression

The yeast transcriptional repressor Tup1, tethered to DNA, represses to strikingly different degrees transcription elicited by members of two classes of activators. Repression in both cases is virtually eliminated by mutation of either member of the cyclin-kinase pair Srb10/11. In contrast, telomeri...

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Autori principali: Zaman, Zafar, Ansari, Aseem Z., Koh, Sang Seok, Young, Richard, Ptashne, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC30175/
https://ncbi.nlm.nih.gov/pubmed/11226276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.041611198
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