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The Status of Exon Skipping as a Therapeutic Approach to Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is associated with mutations in the dystrophin gene that disrupt the open reading frame whereas the milder Becker's form is associated with mutations which leave an in-frame mRNA transcript that can be translated into a protein that includes the N- and C- termi...

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Bibliografische gegevens
Hoofdauteurs: Lu, Qi-Long, Yokota, Toshifumi, Takeda, Shin'ichi, Garcia, Luis, Muntoni, Francesco, Partridge, Terence
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017449/
https://ncbi.nlm.nih.gov/pubmed/20978473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.219
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