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Adenovirus–Retrovirus Hybrid Vectors Achieve Highly Enhanced Tumor Transduction and Antitumor Efficacy In Vivo

Murine leukemia virus (MLV)–based replication-competent retrovirus (RCR) vectors have been shown to mediate efficient, selective, and persistent tumor transduction, thereby achieving significant therapeutic benefit in a wide variety of cancer models. To further augment the efficiency of this strateg...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kubo, Shuji, Haga, Kazunori, Tamamoto, Atsuko, Palmer, Donna J, Ng, Philip, Okamura, Haruki, Kasahara, Noriyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017434/
https://ncbi.nlm.nih.gov/pubmed/20808291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.182
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