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Reverse genetics in eukaryotes

Reverse genetics consists in the modification of the activity of a target gene to analyse the phenotypic consequences. Four main approaches are used toward this goal and will be explained in this review. Two of them are centered on genome alterations. Mutations produced by random chemical or inserti...

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Autores principales: Hardy, Serge, Legagneux, Vincent, Audic, Yann, Paillard, Luc
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press, Ltd 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017359/
https://ncbi.nlm.nih.gov/pubmed/20812916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BC20100038
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