PHASE II AIDS MALIGNANCY CONSORTIUM TRIAL OF TOPICAL HALOFUGINONE IN AIDS-RELATED KAPOSI’S SARCOMA

Using a novel blinded intra-patient vehicle control design, we conducted a phase II study of topically-administered halofuginone, an angiogenesis inhibitor that inhibits collagen type-I and matrix metalloproteinases (MMPs), in patients with AIDS-related Kaposi’s sarcoma (KS). Serial KS biopsies asse...

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Bibliografiske detaljer
Main Authors: Koon, Henry B., Fingleton, Barbara, Lee, Jeannette Y., Geyer, Julia T., Cesarman, Ethel, Parise, Robert A., Egorin, Merrill J., Dezube, Bruce J., Aboulafia, David, Krown, Susan E.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017346/
https://ncbi.nlm.nih.gov/pubmed/21068672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e3181fc0141
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