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The autoimmunity of primary biliary cirrhosis and the clonal selection theory

Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease in which an immune-mediated injury targets the small intrahepatic bile ducts. PBC is further characterized by highly specific serum antimitochondrial autoantibodies (AMA) and autoreactive T cells, a striking female predominance,...

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Hlavní autoři: Selmi, Carlo, Mackay, Ian R., Gershwin, M. Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017230/
https://ncbi.nlm.nih.gov/pubmed/20975735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2010.126
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