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The autoimmunity of primary biliary cirrhosis and the clonal selection theory
Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease in which an immune-mediated injury targets the small intrahepatic bile ducts. PBC is further characterized by highly specific serum antimitochondrial autoantibodies (AMA) and autoreactive T cells, a striking female predominance,...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017230/ https://ncbi.nlm.nih.gov/pubmed/20975735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2010.126 |
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