Feasibility of reconstructed ancestral H5N1 influenza viruses for cross-clade protective vaccine development

Since the reemergence of highly pathogenic H5N1 influenza viruses in humans in 2003, these viruses have spread throughout avian species in Asia, Europe, and Africa. Their sustained circulation has resulted in the evolution of phylogenetically diverse lineages. Viruses from these lineages show consid...

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Bibliographic Details
Main Authors:	Ducatez, Mariette F., Bahl, Justin, Griffin, Yolanda, Stigger-Rosser, Evelyn, Franks, John, Barman, Subrata, Vijaykrishna, Dhanasekaran, Webb, Ashley, Guan, Yi, Webster, Robert G., Smith, Gavin J. D., Webby, Richard J.
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 2011
Subjects:	Biological Sciences
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3017181/ https://ncbi.nlm.nih.gov/pubmed/21173241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012457108
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Feasibility of reconstructed ancestral H5N1 influenza viruses for cross-clade protective vaccine development

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