Feasibility of reconstructed ancestral H5N1 influenza viruses for cross-clade protective vaccine development

Since the reemergence of highly pathogenic H5N1 influenza viruses in humans in 2003, these viruses have spread throughout avian species in Asia, Europe, and Africa. Their sustained circulation has resulted in the evolution of phylogenetically diverse lineages. Viruses from these lineages show consid...

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Detalhes bibliográficos
Main Authors: Ducatez, Mariette F., Bahl, Justin, Griffin, Yolanda, Stigger-Rosser, Evelyn, Franks, John, Barman, Subrata, Vijaykrishna, Dhanasekaran, Webb, Ashley, Guan, Yi, Webster, Robert G., Smith, Gavin J. D., Webby, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017181/
https://ncbi.nlm.nih.gov/pubmed/21173241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012457108
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